Yaron Bram, Ph.D.
Joined January 2015
Dr. Bram completed his Ph.D. at Tel Aviv University, focusing on the initial self-assembly events that occur during the aggregation process of islet amyloid polypeptide (IAPP), often observed in the pancreas of type 2 diabetes patients. He holds a patented method for diabetes treatment, and was the recipient of the Constantiner Fellowship in 2007, as well as the Miriam and Aaron Gutwirth Scholarship for research excellence in 2010.
Dr. Bram’s current research focus is on understanding Hepatitis B virus host-virus interactions during infection. The research utilizes multiple platforms such as stem cell derived hepatocytes, primary human hepatocytes and non-human primate cells to identify key molecular determinants during infection and viral life-cycle.
Duc-Huy Nguyen, Ph.D.
Joined August 2016
Dr. Nguyen completed his PhD at University of Pennsylvania in the department of Chemical and Biomolecular Engineering with Dr. Christopher Chen. During his PhD, he applied his engineering expertise to develop a biomimetic microfluidic platform to reconstitute angiogenesis in vitro and investigate the role of cytoskeletal Cdc42 protein in angiogenic morphogenesis. He also developed a model of vascular invasion in pancreatic cancer to elucidate the cellular interactions between pancreatic ductal adenocarcinoma and blood vessels during cancer metastasis.
His current research focus is to engineer organ on a chip, specifically a liver-on-a-chip that reconstitutes the liver as an organ ex vivo.
Saloni Sinha, Ph.D.
Joined April 2021
Dr. Sinha earned her Ph.D. under the supervision of Prof. Maneesha S. Inamdar in hematopoiesis and stem cell biology from the Jawaharlal Nehru Centre for Advanced Scientific Research, India in December 2019. During her Ph.D., she undertook an integrated approach for deciphering the conserved role of OCIA domain proteins in blood stem cell homeostasis. Her work identified a new mechanism of wild type p53 regulation that maintains quiescence of bone marrow hematopoietic stem cells and how its dysregulation drives myeloproliferative disorder in mice.
After completing her Ph.D., she moved to Yale University, USA for a postdoctoral training in immunobiology, before joining the Schwartz Lab in April 2021. Dr. Sinha is interested in understanding molecular mechanisms during hepatic homeostasis and in different pathophysiological conditions of the liver. In her free time, she enjoys spending time with family, binge-watching Netflix shows, exploring NYC and trying new restaurants.
